Peptide Polymers

OCCLUDIN in Focus

Peptide Polymers

EC1 peptide has non-competible covaspheres binding activity suggesting multiple binding sites or polymerization. Negative staining of occludin extracellular domain 1 peptide confirms that it polymerizes to form fibrils in solution.

Extracellular domain 1 peptide freshly prepared as 10 mM solution (click picture to enlarge).

Extracellular domain 1 peptide as 10 mM solution allowed to incubate at room temperature for 2 weeks (click picture to enlarge).

Extracellular domain 1 peptide as 10 mM solution allowed to incubate at room temperature for months (click picture to enlarge).